HIP1 antibody [4B10]

GeneTex

HIP1 antibody [4B10]

9

We do not recommend use of this product for Rat.

WB: 1:10000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ChIP Chromatin ImmunoPrecipitation, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Monoclonal

4B10

Unconjugated

HIP1

huntingtin interacting protein 1

HIP-I; huntingtin-interacting protein 1; huntingtin-interacting protein I; ILWEQ; SHON; SHONbeta; SHONgamma

Mouse

IgG1

Huntingtin-interacting protein 1

The product of this gene is a membrane-associated protein that colocalizes with huntingtin. This protein has similarities to cytoskeleton proteins and its interaction with huntingtin is thought to play a functional role in the cell filament network. Loss of normal huntingtin-HIP1 interaction in Huntington disease may contribute to a defect in membrane-cytoskeletal integrity in the brain. This gene could help in the understanding of the normal function of huntingtin and also the pathogenesis of Huntington disease. It also has been implicated in the pathogenesis of hematopoietic malignancies. An alternative splice variant of this gene has been described but its full length sequence has not been determined. [provided by RefSeq]

Human, Mouse

-20°C or -80°C,2°C to 8°C

12352203