HIPK3 Polyclonal Antibody

Reddot Biotech

HIPK3 Polyclonal Antibody

5

ELISA, ImmunoHistoChemistry

Research Use Only

Polyclonal

0.6 mg/ml

Unconjugated

HIPK3

homeodomain interacting protein kinase 3

androgen receptor-interacting nuclear protein kinase; ANPK; DYRK6; fas-interacting serine/threonine-protein kinase; FIST; FIST3; homeodomain-interacting protein kinase 3; homolog of protein kinase YAK1; PKY; YAK1

Rabbit

IgG

Serine/threonine-protein kinase involved in transcription regulation, apoptosis and steroidogenic gene expression. Phosphorylates JUN and RUNX2. Seems to negatively regulate apoptosis by promoting FADD phosphorylation. Enhances androgen receptor-mediated transcription. May act as a transcriptional corepressor for NK homeodomain transcription factors. The phosphorylation of NR5A1 activates SF1 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation. In osteoblasts, supports transcription activation: phosphorylates RUNX2 that synergizes with SPEN/MINT to enhance FGFR2-mediated activation of the osteocalcin FGF-responsive element (OCFRE).

Human, Mouse, Rat

-20°C

12352203