Histone H2A.Z antibody
GTX108298
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Zebra Fish
TargetH2AZ1
Overview
- SupplierGeneTex
- Product NameHistone H2A.Z antibody
- Delivery Days Customer9
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.52 mg/ml
- ConjugateUnconjugated
- Gene ID3015
- Target nameH2AZ1
- Target descriptionH2A.Z variant histone 1
- Target synonymsH2A histone family member Z; H2A.z; H2A.Z-1; H2A/z; H2AFZ; H2AZ; H2AZ histone; histone H2A.Z
- HostRabbit
- IsotypeIgG
- Scientific DescriptionHistones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a replication-independent member of the histone H2A family that is distinct from other members of the family. Studies in mice have shown that this particular histone is required for embryonic development and indicate that lack of functional histone H2A leads to embryonic lethality. [provided by RefSeq]
- ReactivityHuman, Zebra Fish
- Storage Instruction2°C to 8°C,-20°C or -80°C
- UNSPSC12352203
References
- The Histone Chaperone FACT Coordinates H2A.X-Dependent Signaling and Repair of DNA Damage. Piquet S et al., 2018 Dec 6, Mol CellRead more