hnRNP F antibody [3H4]
GTX26095
Overview
- SupplierGeneTex
- Product NamehnRNP F antibody [3H4]
- Delivery Days Customer9
- Antibody SpecificityHuman hnRNP-F. Reacts with a band in the region of 47-50kDa. Cross Reactivity undeterminined
- Application Supplier NoteRecommended Starting Dilutions:For WB: Use at 1:500Optimal dilutions should be determined experimentally by the researcher.
- ApplicationsWestern Blot, ELISA
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone ID3H4
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID3185
- Target nameHNRNPF
- Target descriptionheterogeneous nuclear ribonucleoprotein F
- Target synonymsheterogeneous nuclear ribonucleoprotein F; HnRNP F protein; HNRPF; mcs94-1; nucleolin-like protein mcs94-1; OK/SW-cl.23
- HostMouse
- IsotypeIgG1
- Protein IDP52597
- Protein NameHeterogeneous nuclear ribonucleoprotein F
- Scientific DescriptionThis gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins that complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and regulate alternative splicing, polyadenylation, and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has three repeats of quasi-RRM domains that bind to RNAs which have guanosine-rich sequences. This protein is very similar to the family member hnRPH. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008]
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Serine/Arginine-Rich Splicing Factor 3 and Heterogeneous Nuclear Ribonucleoprotein A1 Regulate Alternative RNA Splicing and Gene Expression of Human Papillomavirus 18 through Two Functionally Distinguishable cis Elements. Ajiro M et al., 2016 Oct 15, J VirolRead more
- Splicing factor hnRNPH drives an oncogenic splicing switch in gliomas. Lefave CV et al., 2011 Sep 13, EMBO JRead more