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hnRNP F antibody [3H4]

GTX26095
GeneTex
ApplicationsWestern Blot, ELISA
Product group Antibodies
ReactivityHuman
TargetHNRNPF
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Overview

  • Supplier
    GeneTex
  • Product Name
    hnRNP F antibody [3H4]
  • Delivery Days Customer
    9
  • Antibody Specificity
    Human hnRNP-F. Reacts with a band in the region of 47-50kDa. Cross Reactivity undeterminined
  • Application Supplier Note
    Recommended Starting Dilutions:For WB: Use at 1:500Optimal dilutions should be determined experimentally by the researcher.
  • Applications
    Western Blot, ELISA
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    3H4
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID3185
  • Target name
    HNRNPF
  • Target description
    heterogeneous nuclear ribonucleoprotein F
  • Target synonyms
    heterogeneous nuclear ribonucleoprotein F; HnRNP F protein; HNRPF; mcs94-1; nucleolin-like protein mcs94-1; OK/SW-cl.23
  • Host
    Mouse
  • Isotype
    IgG1
  • Protein IDP52597
  • Protein Name
    Heterogeneous nuclear ribonucleoprotein F
  • Scientific Description
    This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins that complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and regulate alternative splicing, polyadenylation, and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has three repeats of quasi-RRM domains that bind to RNAs which have guanosine-rich sequences. This protein is very similar to the family member hnRPH. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008]
  • Reactivity
    Human
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Serine/Arginine-Rich Splicing Factor 3 and Heterogeneous Nuclear Ribonucleoprotein A1 Regulate Alternative RNA Splicing and Gene Expression of Human Papillomavirus 18 through Two Functionally Distinguishable cis Elements. Ajiro M et al., 2016 Oct 15, J Virol
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  • Splicing factor hnRNPH drives an oncogenic splicing switch in gliomas. Lefave CV et al., 2011 Sep 13, EMBO J
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