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Homocarbonyltopsentin

HY-117389
MedChem Express
CAS Number172286-77-0
Product group Chemicals
Estimated Purity99.88
Molecular Weight370.36
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Homocarbonyltopsentin [172286-77-0]
  • Delivery Days Customer
    10
  • CAS Number
    172286-77-0
  • Certification
    Research Use Only
  • Estimated Purity
    99.88
  • Molecular Formula
    C21H14N4O3
  • Molecular Weight
    370.36
  • Scientific Description
    Homocarbonyltopsentin (PK4C9) is a small-molecule TSL2 -binding compound, binds to pentaloop conformations of TSL2 and promotes a shift to triloop conformations that display enhanced SMN2 exon 7 (E7) splicing with EC 50 value of 16 microM [1] .
  • SMILES
    O=C(C1=NC=C(C(C2=CNC3=C2C=CC=C3)=O)N1)C4=CNC5=C4C=CC(O)=C5
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200

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