CgoaEGY7NL2ELMGeAAAAAPT-csI756.png
HPK1-IN-7 [2320462-65-3]
T9470
Overview
- SupplierTargetMol Chemicals
- Product NameHPK1-IN-7 [2320462-65-3]
- Delivery Days Customer4
- CAS Number2320462-65-3
- Category SupplierChemical
- CertificationResearch Use Only
- Chemical NameHPK1-IN-7
- Molecular FormulaC24H22N6O4
- Molecular Weight458.47
- Scientific DescriptionHPK1-IN-7 is an orally active HPK1 inhibitor. It shows selectivity against IRAK4 (59 nM) and GLK (140 nM).
- Shelf life instruction3 years
- SMILESCC1(C)OC(=O)c2ccc(Nc3ncc(-c4nnco4)c(N[C@H](CO)c4ccccc4)n3)cc12
- Storage Instruction-20°C
- UNSPSC51202000
References
- Degnan AP, et al. Discovery of Orally Active Isofuranones as Potent, Selective Inhibitors of Hematopoetic Progenitor Kinase 1. ACS Med Chem Lett. 2021;12(3):443-450. Published 2021 Feb 19.Read more