HSD3B7 antibody, Internal

GeneTex

HSD3B7 antibody, Internal

10

Western Blot

Research Use Only

Polyclonal

0.5-1 mg/ml

Rabbit

IgG

This gene encodes an enzyme which is involved in the initial stages of the synthesis of bile acids from cholesterol and a member of the short-chain dehydrogenase/reductase superfamily. The encoded protein is a membrane-associated endoplasmic reticulum protein which is active against 7-alpha hydrosylated sterol substrates. Mutations in this gene are associated with a congenital bile acid synthesis defect which leads to neonatal cholestasis, a form of progressive liver disease. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008]

Human

2°C to 8°C,-20°C

12352203