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hSMG-1 inhibitor 11j [1402452-15-6]

hSMG-1 inhibitor 11j [1402452-15-6]

T8884
TargetMol Chemicals
CAS Number1402452-15-6
DownloadMSDS
Product group Chemicals
Estimated Purity99.29%
Molecular Weight566.07
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    hSMG-1 inhibitor 11j [1402452-15-6]
  • Delivery Days Customer
    9
  • CAS Number
    1402452-15-6
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    hSMG-1 inhibitor 11j
  • Estimated Purity
    99.29%
  • Molecular Formula
    C27H28ClN7O3S
  • Molecular Weight
    566.07
  • Scientific Description
    hSMG-1 inhibitor 11j is a pyrimidine derivative. hSMG-1 inhibitor 11j is a potent and selective inhibitor of hSMG-1, IC50 = 0.11 nM. hSMG-1 inhibitor 11j exhibits >455-fold selectivity for hSMG-1 over mTOR (IC50=50 nM), PI3Kalpha/gamma (IC50=92/60 nM) and CDK1/CDK2 (IC50=32/7.1 microM). hSMG-1 inhibitor 11j can be used for the research of cancer.
  • Shelf life instruction
    3 years
  • SMILES
    CCN(CC)S(=O)(=O)c1cc(Nc2nccc(n2)-c2ccnc(c2)-c2ccc(NC(=O)NC)cc2)ccc1Cl
  • Storage Instruction
    -20°C
  • UNSPSC
    51202000

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