HSP60 antibody

Name: HSP60 antibody
SKU: GTX110089_G10
Availability: BackOrder

GTX110089

ApplicationsImmunoFluorescence, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

DownloadDatasheet

Product group Antibodies

TargetHSPD1

Overview

Supplier
GeneTex
Product Name
HSP60 antibody
Delivery Days Customer
9
Application Supplier Note
WB: 1:5000-1:20000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Applications
ImmunoFluorescence, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Certification
Research Use Only
Clonality
Polyclonal
Concentration
0.3 mg/ml
Conjugate
Unconjugated
Gene ID3329
Target name
HSPD1
Target description
heat shock protein family D (Hsp60) member 1
Target synonyms
60 kDa chaperonin; 60 kDa heat shock protein, mitochondrial; chaperonin 60; CPN60; epididymis secretory sperm binding protein; GROEL; heat shock 60kDa protein 1 (chaperonin); heat shock protein 65; HLD4; HSP60; HSP-60; HSP65; HuCHA60; mitochondrial matrix protein P1; P60 lymphocyte protein; short heat shock protein 60 Hsp60s1; SPG13
Host
Rabbit
Isotype
IgG
Protein IDP10809
Protein Name
60 kDa heat shock protein, mitochondrial
Scientific Description
This gene encodes a member of the chaperonin family. The encoded mitochondrial protein may function as a signaling molecule in the innate immune system. This protein is essential for the folding and assembly of newly imported proteins in the mitochondria. This gene is adjacent to a related family member and the region between the 2 genes functions as a bidirectional promoter. Two pseudogenes, both located on chromosome 8, have been associated with this gene. Two transcript variants encoding the same protein have been identified for this gene. Mutations associated with this gene cause autosomal recessive spastic paraplegia 13. [provided by RefSeq]
Storage Instruction
-20°C or -80°C,2°C to 8°C
UNSPSC
12352203

References

The rheumatoid arthritis drug auranofin lowers leptin levels and exerts antidiabetic effects in obese mice.
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Bicalutamide Exhibits Potential to Damage Kidney via Destroying Complex I and Affecting Mitochondrial Dynamics. Chen KC et al., 2021 Dec 27, J Clin Med
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Anesthesia-Sepsis-Associated Alterations in Liver Gene Expression Profiles and Mitochondrial Oxidative Phosphorylation Complexes. Osuru HP et al., 2020, Front Med (Lausanne)
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Functional proteomic analysis reveals that fungal immunomodulatory protein reduced expressions of heat shock proteins correlates to apoptosis in lung cancer cells. Lin TY et al., 2021 Jan, Phytomedicine
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Enrichment of microsomes from Chinese hamster ovary cells by subcellular fractionation for its use in proteomic analysis. Perez-Rodriguez S et al., 2020, PLoS One
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NIX compensates lost role of parkin in cd-induced mitophagy in HeLa cells through phosphorylation. Naeem S et al., 2020 Jun 15, Toxicol Lett
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Bisphenol AF promotes inflammation in human white adipocytes. Chernis N et al., 2020 Jan 1, Am J Physiol Cell Physiol
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Post mortem examination of Parkinsons disease brains suggests decline in mitochondrial biomass, reversed by deep brain stimulation of subthalamic nucleus. Mallach A et al., 2019 Jun, FASEB J
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PE_PGRS3 of Mycobacterium tuberculosis is specifically expressed at low phosphate concentration, and its arginine-rich C-terminal domain mediates adhesion and persistence in host tissues when expressed in Mycobacterium smegmatis. De Maio F et al., 2018 Dec, Cell Microbiol
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Aqueous extracts of Paeonia suffruticosa modulates mitochondrial proteostasis by reactive oxygen species-induced endoplasmic reticulum stress in pancreatic cancer cells. Liu YH et al., 2018 Jul 15, Phytomedicine
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HSP60 antibody

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Overview

References

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