HSPD1 / HSP60 Antibody (clone LK1)

LifeSpan BioSciences

HSPD1 / HSP60 Antibody (clone LK1)

23

Human HSPD1 / HSP60

This antibody recognizes a 60kDa protein, identified as the heat shock protein 60. The antibodys epitope is localized between amino acids 383-447 of human HSP60. A wide variety of environmental and pathophysiological stressful conditions trigger the synthesis of a family of proteins known as heat shock proteins (hsps), more appropriately called as stress response proteins (srps). HSP60 is a potential antigen in a number of autoimmune diseases. In human arthritis and in experimentally induced arthritis in animals, disease development coincides with the development of immune reactivity directed against not only bacterial HSP60, but also against its mammalian homolog. Clone LK1 antibody, unlike LK2 antibody, recognizes only the mammalian (not bacterial) HSP60 and is useful in distinguishing HSP60 from mammals and bacteria. ELISA: Order BSA-free format for coating.. ELISA, Flo (0.5 - 1 µg/10E6 cells), IF (0.5 - 1 µg/ml), IHC, IHC-P (0.5 - 1 µg/ml), IP, WB (0.25 - 0.5 µg/ml) This antibody recognizes a 60kDa protein, identified as the heat shock protein 60. The antibodys epitope is localized between amino acids 383-447 of human HSP60. A wide variety of environmental and pathophysiological stressful conditions trigger the synthesis of a family of proteins known as heat shock proteins (hsps), more appropriately called as stress response proteins (srps). HSP60 is a potential antigen in a number of autoimmune diseases. In human arthritis and in experimentally induced arthritis in animals, disease development coincides with the development of immune reactivity directed against not only bacterial HSP60, but also against its mammalian homolog. Clone LK1 antibody, unlike LK2 antibody, recognizes only the mammalian (not bacterial) HSP60 and is useful in distinguishing HSP60 from mammals and bacteria. ELISA: Order BSA-free format for coating.

Flow Cytometry, ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ELISA, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Monoclonal

LK1

0.2 mg/ml

Unconjugated

...

HSPD1

heat shock protein family D (Hsp60) member 1

60 kDa chaperonin; 60 kDa heat shock protein, mitochondrial; chaperonin 60; CPN60; epididymis secretory sperm binding protein; GROEL; heat shock 60kDa protein 1 (chaperonin); heat shock protein 65; HLD4; HSP60; HSP-60; HSP65; HuCHA60; mitochondrial matrix protein P1; P60 lymphocyte protein; short heat shock protein 60 Hsp60s1; SPG13

Mouse

IgG1

Bacteria, Bovine, Canine, Chicken, Drosophila, Hamster, Human, Monkey, Mouse, Parasite, Plant, Porcine, Rabbit, Rat, Sheep, Xenopus

2°C to 8°C

12352203