The figure shows a typical standard curve for the bioactive human Sclerostin ELISA. The immunoassay is calibrated against recombinant human bioactive Sclerostin.
The figure shows a typical standard curve for the bioactive human Sclerostin ELISA. The immunoassay is calibrated against recombinant human bioactive Sclerostin.
bioactive Sclerostin ELISA
BI-20472
Overview
- SupplierBiomedica
- Product NameHuman bioactive Sclerostin ELISA
- Delivery Days Customer7
- ApplicationsELISA
- Applications SupplierELISA
- Assay Detection Range10-320 pmol/l
- Assay Precisionintra-assay: 1%, inter-assay: 5%
- Assay Sample Typeserum, EDTA plasma and citrate plasma
- Assay Sensitivity1.9 pmol/l
- Assay Specificityhuman bioactive Sclerostin
- Assay Test PrincipleSandwich ELISA
- Assay Time3.5h
- Category SupplierAssay
- CertificationResearch Use Only
- Scientific DescriptionProduct Characteristics: The Biomedica human bioactive Sclerostin (SOST) Sandwich ELISA kit is a quick day test intended for the quantitative measurement of bioactive Sclerostin levels in human serum and plasma samples (EDTA and citrate). The bioactive SOST ELISA specifically recognizes the Sclerostin osteoclast interacting (functional) domain. Target Information: Canonical Wnt-signalling plays an important role in the regulation of bone homeostasis by promoting the development of osteoblasts. Negative regulators of the Wnt pathway are important therapeutic targets for the treatment of diseases with enhanced bone resorption. One of these molecules is Sclerostin, a 22.5 kD secreted glycoprotein, which acts by binding to the Wnt-coreceptor LRP5 thus preventing the binding of Wnt molecules.
- Storage Instruction2-8°C
- UNSPSC41116133
References
- Biomedica citations for human bioactive Sclerostin ELISA, BI-20472Read more