The figure shows a typical standard curve for the human Sclerostin ELISA. The immunoassay is calibrated against human recombinant Sclerostin peptide.

Sclerostin ELISA

BI-20492

Assay Sample Typeserum, EDTA plasma, citrate plasma, heparın plasma, urine, cell culture supernatant

Product group Assays

Overview

Supplier
Biomedica
Product Name
Human Sclerostin ELISA
Delivery Days Customer
7
Applications
ELISA
Applications Supplier
ELISA
Assay Detection Range
15-240 pmol/l
Assay Precision
intra-assay: 7%, inter-assay: 10%
Assay Sample Type
serum, EDTA plasma, citrate plasma, heparın plasma, urine, cell culture supernatant
Assay Sensitivity
3.2 pmol/l
Assay Specificity
human total Sclerostin
Assay Test Principle
Sandwich ELISA
Assay Time
overnight assay
Category Supplier
Assay
Certification
Research Use Only
Scientific Description
Product Characteristics: The Biomedica human Sclerostin (SOST) Sandwich ELISA kit is a test that is intended for the quantitative measurement of Sclerostin levels in human serum and plasma samples (EDTA, heparin). The Biomedica Sclerostin ELISA is with more than 180 references the most cited Sclerostin ELISA worldwide. Target Information: Canonical Wnt-signalling plays an important role in the regulation of bone homeostasis by promoting the development of osteoblasts. Negative regulators of the Wnt pathway are important therapeutic targets for the treatment of diseases with enhanced bone resorption. One of these molecules is Sclerostin, a 22.5 kD secreted glycoprotein, which acts by binding to the Wnt-coreceptor LRP5 thus preventing the binding of Wnt molecules.
Storage Instruction
2-8°C
UNSPSC
41116133