Human Sclerostin ELISA Kit

Arigo Biolaboratories

Human Sclerostin ELISA Kit

23

ELISA

Intra-Assay CV: 5.5% Inter-Assay CV: 6.5%

15.6 pg/ml

There is no detectable cross-reactivity with other relevant proteins.

~ 5 hours

Research Use Only

Sclerostin is a secreted glycoprotein with a C-terminal cysteine knot-like (CTCK) domain and sequence similarity to the DAN (differential screening-selected gene aberrative in neuroblastoma) family of bone morphogenetic protein (BMP) antagonists. Loss-of-function mutations in this gene are associated with an autosomal-recessive disorder, sclerosteosis, which causes progressive bone overgrowth. A deletion downstream of this gene, which causes reduced sclerostin expression, is associated with a milder form of the disorder called van Buchem disease. [provided by RefSeq, Jul 2008]

2°C to 8°C

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