3microg Human TCL1A protein (GTX67964-pro) by SDS-PAGE under reducing condition and visualized by coomassie blue stain.
3microg Human TCL1A protein (GTX67964-pro) by SDS-PAGE under reducing condition and visualized by coomassie blue stain.
Human TCL1A protein
GTX67964-PRO
Overview
- SupplierGeneTex
- Product NameHuman TCL1A protein
- Delivery Days Customer9
- CertificationResearch Use Only
- Concentration1 mg/ml
- ConjugateUnconjugated
- FormulationLiquid
- Protein IDP56279
- Protein NameT-cell leukemia/lymphoma protein 1A
- Scientific DescriptionOverexpression of the TCL1 gene in humans has been implicated in the development of mature T cell leukemia, in which chromosomal rearrangements bring the TCL1 gene in close proximity to the T-cell antigen receptor (TCR)-alpha (MIM 186880) or TCR-beta (MIM 186930) regulatory elements (summarized by Virgilio et al., 1998 [PubMed 9520462]). In normal T cells TCL1 is expressed in CD4-/CD8- cells, but not in cells at later stages of differentiation. TCL1 functions as a coactivator of the cell survival kinase AKT (MIM 164730) (Laine et al., 2000 [PubMed 10983986]).[supplied by OMIM, Jul 2010]
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352202