Hypothemycin

MedChem Express

Hypothemycin [76958-67-3]

10

76958-67-3

Research Use Only

98.0

C19H22O8

378.37

Hypothemycin, a fungal polyketide, is a multikinase inhibitor with Kis of 10/70 nM, 17/38 nM, 90 nM, 900 nM/1.5 microM, and 8.4/2.4 microM for VEGFR2/VEGFR1, MEK1/MEK2, FLT-3, PDGFRbeta/PDGFRalpha, and ERK1/ERK2, respectively[1][2].

COC1=CC(O)=C(C(O[C@@H](C)C/C=C\C2=O)=O)C([C@@H](O3)[C@@]3([H])C[C@H](O)[C@@H]2O)=C1

-20°C

12352200