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IACS-010759 hydrochloride [1807523-99-4]

IACS-010759 hydrochloride [1807523-99-4]

T27568
TargetMol Chemicals
CAS Number1807523-99-4
Product group Chemicals
Molecular Weight599.03
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    IACS-010759 hydrochloride
  • Delivery Days Customer
    14
  • CAS Number
    1807523-99-4
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    IACS-010759 hydrochloride
  • Molecular Formula
    C25H26ClF3N6O4S
  • Molecular Weight
    599.03
  • Scientific Description
    IACS-010759 is a potent inhibitor of complex I of OXPHOS with orally bioavailable. IACS-10759 effectively inhibits ATP production and oxygen consumption in isolated mitochondria, and inhibits the conversion of NADH to NAD+ in immunoprecipitated complex I in low nM range. IACS-10759 shows significant efficacy in multiple tumor indications both in vitro and in vivo.
  • Shelf life instruction
    3 years
  • SMILES
    Cl.Cc1nc(nn1Cc1cccc(c1)N1CCC(CC1)S(C)(=O)=O)-c1nc(no1)-c1ccc(OC(F)(F)F)cc1
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

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