IARS antibody

GeneTex

IARS antibody

9

WB: 1:1000-1:10000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

ImmunoPrecipitation, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Polyclonal

0.45 mg/ml

Unconjugated

IARS1

isoleucyl-tRNA synthetase 1

GRIDHH; IARS; ILERS; ILRS; IRS; isoleucine tRNA ligase 1, cytoplasmic; isoleucine--tRNA ligase, cytoplasmic; PRO0785

Rabbit

IgG

Isoleucine--tRNA ligase, cytoplasmic

Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAS, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Isoleucine-tRNA synthetase belongs to the class-I aminoacyl-tRNA synthetase family and has been identified as a target of autoantibodies in the autoimmune disease polymyositis/dermatomyositis. Two alternatively spliced variants have been isolated that represent alternate 5 UTRs. [provided by RefSeq]

Human, Rat

-20°C or -80°C,2°C to 8°C

12352203