The image on the left is immunohistochemistry of paraffin-embedded Human tonsil tissue using CSB-PA123586(ICOS Antibody) at dilution 1/17, on the right is treated with fusion protein. (Original magnification: x200)
The image on the left is immunohistochemistry of paraffin-embedded Human tonsil tissue using CSB-PA123586(ICOS Antibody) at dilution 1/17, on the right is treated with fusion protein. (Original magnification: x200)
ICOS Antibody
CSB-PA123586
ApplicationsELISA, ImmunoHistoChemistry
Product group Antibodies
TargetICOS
Overview
- SupplierCusabio
- Product NameICOS Antibody
- Delivery Days Customer20
- ApplicationsELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID29851
- Target nameICOS
- Target descriptioninducible T cell costimulator
- Target synonymsactivation-inducible lymphocyte immunomediatory molecule; AILIM; CD278; CVID1; inducible costimulator; inducible T-cell costimulator; inducible T-cell co-stimulator
- HostRabbit
- IsotypeIgG
- Protein IDQ9Y6W8
- Protein NameInducible T-cell costimulator
- Scientific DescriptionThe protein encoded by this gene belongs to the CD28 and CTLA-4 cell-surface receptor family. It forms homodimers and plays an important role in cell-cell signaling, immune responses, and regulation of cell proliferation. Enhances all basic T-cell responses to a foreign antigen, namely proliferation, secretion of lymphokines, up-regulation of molecules that mediate cell-cell interaction, and effective help for antibody secretion by B-cells. Essential both for efficient interaction between T and B-cells and for normal antibody responses to T-cell dependent antigens. Does not up-regulate the production of interleukin-2, but superinduces the synthesis of interleukin-10. Prevents the apoptosis of pre-activated T-cells. Plays a critical role in CD40-mediated class switching of immunoglobin isotypes.
- Storage Instruction-20°C or -80°C
- UNSPSC12352203
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