Western Blot analysis of 293T and Jurkat cell, Human fetal muscle tissue using IDH2 Polyclonal Antibody at dilution of 1:600
Western Blot analysis of 293T and Jurkat cell, Human fetal muscle tissue using IDH2 Polyclonal Antibody at dilution of 1:600
IDH2 Polyclonal Antibody
E-AB-15121
Product group Antibodies
Overview
- SupplierElabscience
- Product NameIDH2 Polyclonal Antibody
- Delivery Days Customer12
- Applications SupplierELISA WB IHC
- CertificationResearch Use Only
- Concentration0.4mg/ml
- Scientific DescriptionIsocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. Each NADP(+)-dependent isozyme is a homodimer. The protein encoded by this gene is the NADP(+)-dependent isocitrate dehydrogenase found in the mitochondria. It plays a role in intermediary metabolism and energy production. This protein may tightly associate or interact with the pyruvate dehydrogenase complex. Alternative splicing results in multiple transcript variants.
- UNSPSC12352203