IGF-I R, Human (sf9, His-GST)

MedChem Express

IGF-I R, Human (sf9, His-GST)

10

Research Use Only

IGF1R

insulin like growth factor 1 receptor

CD221, IGFIR, IGFR, JTK13, insulin-like growth factor 1 receptor, IGF-I receptor

Insulin-like growth factor 1 receptor

IGF-I receptor (IGF1R) mediates insulin-like growth factor effects, binding strongly to IGF1. Activation triggers PI3K-AKT/PKB and Ras-MAPK pathways, influencing cell survival, protein synthesis, and proliferation. IGF1R also signals through JAK/STAT, inhibiting JNK activation. Hybrid receptors show variable binding to IGF1 and insulin. IGF-I R Protein, Human (sf9, His-GST) is the recombinant human-derived IGF-I R protein, expressed by Sf9 insect cells , with N-His, N-GST labeled tag.

41116100

Human