Western blot analysis of IGF1R phosphorylation expression in Insulin treated 293 whole cell lysates,The lane on the left is treated with the antigen-specific peptide.
Western blot analysis of IGF1R phosphorylation expression in Insulin treated 293 whole cell lysates,The lane on the left is treated with the antigen-specific peptide.
IGF1R beta (phospho Tyr1131) / Insulin Receptor beta (phospho Tyr1146) antibody
GTX52315
ApplicationsImmunoPrecipitation, Western Blot, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetIGF1R
Overview
- SupplierGeneTex
- Product NameIGF1R (phospho Tyr1131) / Insulin Receptor (phospho Tyr1146) antibody
- Delivery Days Customer9
- Antibody SpecificityTyr1161 in full-length IGF-1R is equivalent toTyr1131 in signal peptide cleaved IGF1R, and Tyr1185 in full-length Insulin Receptor is equivalent to Tyr1146 in signal peptide cleaved Insulin Receptor.
- Application Supplier NoteWB 1:500-1:2000, IHC 1:50-1:200, IP
- ApplicationsImmunoPrecipitation, Western Blot, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID3480
- Target nameIGF1R
- Target descriptioninsulin like growth factor 1 receptor
- Target synonymsCD221; IGF-I receptor; IGFIR; IGFR; insulin-like growth factor 1 receptor; JTK13; soluble IGF1R variant 1; soluble IGF1R variant 2
- HostRabbit
- IsotypeIgG
- Protein IDP08069
- Protein NameInsulin-like growth factor 1 receptor
- Scientific DescriptionThis receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2014]
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203