ProductsBack/IGF1R beta (phospho Tyr1131) / Insulin Receptor beta (phospho Tyr1146) antibody

WB analysis of 293 cells untreated (left) or treated(right) with Insulin using GTX79046 IGF1R beta (phospho Tyr1131) / Insulin Receptor beta (phospho Tyr1146) antibody.

IGF1R beta (phospho Tyr1131) / Insulin Receptor beta (phospho Tyr1146) antibody

GTX79046

ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Product group Antibodies

ReactivityHuman

TargetIGF1R

Overview

Supplier
GeneTex
Product Name
IGF1R beta (phospho Tyr1131) / Insulin Receptor beta (phospho Tyr1146) antibody
Delivery Days Customer
9
Application Supplier Note
WB: 1:500 - 1:1000. IHC-P: 1:50 - 1:100. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Applications
Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Certification
Research Use Only
Clonality
Polyclonal
Conjugate
Unconjugated
Gene ID3480
Target name
IGF1R
Target description
insulin like growth factor 1 receptor
Target synonyms
CD221, IGFIR, IGFR, JTK13, insulin-like growth factor 1 receptor, IGF-I receptor
Host
Rabbit
Isotype
IgG
Protein IDP08069
Protein Name
Insulin-like growth factor 1 receptor
Scientific Description
This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2014]
Reactivity
Human
Storage Instruction
-20°C or -80°C,2°C to 8°C
UNSPSC
12352203