IGF1R beta (phospho Tyr1135 / Tyr1136) / Insulin Receptor beta (phospho Tyr1150 / Tyr1151) antibody

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IGF1R (phospho Tyr1135 / Tyr1136) / Insulin Receptor (phospho Tyr1150 / Tyr1151) antibody

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This antibody is raised against a synthetic peptide around phosphorylated Tyr1135 / Tyr1136 of IGF1R (signal peptide cleaved form), which is identical to the sequence around phosphorylated Tyr1150 / Tyr1151 of Insulin Receptor (signal peptide cleaved form

WB: 1:500-1:1000. ICC/IF: 1:100-1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

ImmunoFluorescence, Western Blot, ImmunoCytoChemistry

Research Use Only

Polyclonal

1 mg/ml

Unconjugated

Liquid

IGF1R

insulin like growth factor 1 receptor

CD221; IGF-I receptor; IGFIR; IGFR; insulin-like growth factor 1 receptor; JTK13; soluble IGF1R variant 1; soluble IGF1R variant 2

Rabbit

IgG

Phosphorylated

Insulin-like growth factor 1 receptor

This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2014]

Human

-20°C or -80°C,2°C to 8°C

12352203