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IGFBP1 antibody

Name: IGFBP1 antibody
SKU: GTX129006_G10
Availability: BackOrder

GTX129006

ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry

Product group Antibodies

TargetIGFBP1

Overview

Supplier
GeneTex
Product Name
IGFBP1 antibody
Delivery Days Customer
9
Application Supplier Note
WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IP: 1:100-1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Applications
ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry
Certification
Research Use Only
Clonality
Polyclonal
Concentration
1 mg/ml
Conjugate
Unconjugated
Gene ID3484
Target name
IGFBP1
Target description
insulin like growth factor binding protein 1
Target synonyms
AFBP, IBP1, IGF-BP25, PP12, hIGFBP-1, insulin-like growth factor-binding protein 1, IBP-1, IGF-binding protein 1, IGFBP-1, alpha-pregnancy-associated endometrial globulin, amniotic fluid binding protein, binding protein-25, binding protein-26, binding protein-28, growth hormone independent-binding protein, placental protein 12
Host
Rabbit
Isotype
IgG
Protein IDP08833
Protein Name
Insulin-like growth factor-binding protein 1
Scientific Description
This gene is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain. The protein binds both insulin-like growth factors (IGFs) I and II and circulates in the plasma. Binding of this protein prolongs the half-life of the IGFs and alters their interaction with cell surface receptors. [provided by RefSeq]
Storage Instruction
-20°C or -80°C,2°C to 8°C
UNSPSC
12352203

Lin JC, Liu TP, Chen YB, et al. PF-429242 exhibits anticancer activity in hepatocellular carcinoma cells via FOXO1-dependent autophagic cell death and IGFBP1-dependent anti-survival signaling. Am J Cancer Res. 2023,13(9):4125-4144.
Read this paper
Chiu YF, Wu CC, Kuo MH, et al. Critical role of SOX2-IGF2 signaling in aggressiveness of bladder cancer. Sci Rep. 2020,10(1):8261. doi: 10.1038/s41598-020-65006-z
Read this paper