Sandwich ELISA using RM121 as the capture antibody (100ng/well), and Biotinylated anti-human light chains (k+l) antibody RM129 (0.2ug/mL) as the detection antibody, followed by an alkaline phosphatase conjugated streptavidin.
IgM (human) Matched Antibody Pair
REV-31-1023-MK
Overview
- SupplierRevMAb Biosciences
- Product NameIgM (human) Matched Antibody Pair
- Delivery Days Customer5
- Antibody SpecificityThe antibody pair detects only human IgM. It does not react to monkey (Cyno or Rhesus) IgG, mouse IgG, rat IgG, or goat IgG. There is no cross reactivity to any other immunoglobulins or IgG subclasses.
- ApplicationsELISA
- CertificationResearch Use Only
- Protein IDP01871
- Protein NameImmunoglobulin heavy constant mu
- Scientific DescriptionThe Human IgM Matched Antibody Pairs is specific to Human IgM and has been demonstrated through ELISA. It does not cross-react to IgG from Non-Human Primate species (Rhesus and Cynomologus macaques), or mouse, rat or goat immunoglobulin. The kit can be used for the detection of therapeutic antibodies from samples obtained from experimental animals to provide accurate pharmacokinetic (PK) data. Immunoglobulin M (IgM) is one of several isotypes of antibody (also known as immunoglobulin) that are produced by vertebrates. IgM is the largest antibody, and it is the first antibody to appear in the response to initial exposure to an antigen. In the case of humans and other mammals that have been studied, the spleen, where plasmablasts responsible for antibody production reside, is the major site of specific IgM production. - The Human IgM Matched Antibody Pairs is specific to Human IgM and has been demonstrated through ELISA. It does not cross-react to IgG from Non-Human Primate species (Rhesus and Cynomologus macaques), or mouse, rat or goat immunoglobulin. The kit can be used for the detection of therapeutic antibodies from samples obtained from experimental animals to provide accurate pharmacokinetic (PK) data.Immunoglobulin M (IgM) is one of several isotypes of antibody (also known as immunoglobulin) that are produced by vertebrates. IgM is the largest antibody, and it is the first antibody to appear in the response to initial exposure to an antigen. In the case of humans and other mammals that have been studied, the spleen, where plasmablasts responsible for antibody production reside, is the major site of specific IgM production.
- ReactivityHuman
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12352203