Ikaros antibody

GeneTex

Ikaros antibody

9

WB: 1:500-1:3000. IP: 1:100-1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

ImmunoPrecipitation, Western Blot, ChIP Chromatin ImmunoPrecipitation

Research Use Only

Polyclonal

0.38 mg/ml

Unconjugated

IKZF1

IKAROS family zinc finger 1

CVID13, Hs.54452, IK1, IKAROS, LYF1, LyF-1, PPP1R92, PRO0758, ZNFN1A1, DNA-binding protein Ikaros, CLL-associated antigen KW-6, ikaros family zinc finger protein 1, lymphoid transcription factor LyF-1, protein phosphatase 1, regulatory subunit 92, zinc finger protein, subfamily 1A, 1 (Ikaros)

Rabbit

IgG

DNA-binding protein Ikaros

Transcription regulator of hematopoietic cell differentiation. Binds gamma-satellite DNA. Binds with higher affinity to gamma satellite A. Plays a role in the development of lymphocytes, B- and T-cells. Binds and activates the enhancer (delta-A element) of the CD3-delta gene. Repressor of the TDT (terminal deoxynucleotidyltransferase) gene during thymocyte differentiation. Regulates transcription through association with both HDAC-dependent and HDAC-independent complexes. Targets the 2 chromatin-remodeling complexes, NuRD and BAF (SWI/SNF), in a single complex (PYR complex), to the beta-globin locus in adult erythrocytes. Increases normal apoptosis in adult erythroid cells. Confers early temporal competence to retinal progenitor cells (RPCs).

-20°C or -80°C,2°C to 8°C

12352203