![WB analysis of Jurkat cell lysate using GTX82797 IKB beta antibody [7B4]. WB analysis of Jurkat cell lysate using GTX82797 IKB beta antibody [7B4].](https://www.genetex.com/upload/website/prouct_img/normal/GTX82797/GTX82797_20170912_WB_w_23061322_464.webp)
WB analysis of Jurkat cell lysate using GTX82797 IKB beta antibody [7B4].
IKB beta antibody [7B4]
GTX82797
ApplicationsWestern Blot, ELISA
Product group Antibodies
ReactivityHuman, Rat
TargetNFKBIB
Overview
- SupplierGeneTex
- Product NameIKB beta antibody [7B4]
- Delivery Days Customer9
- Application Supplier NoteWB: 1/500 - 1/2000. ELISA: 1/10000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot, ELISA
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone ID7B4
- ConjugateUnconjugated
- Gene ID4793
- Target nameNFKBIB
- Target descriptionNFKB inhibitor beta
- Target synonymsIKBB, TRIP9, NF-kappa-B inhibitor beta, I-kappa-B-beta, NF-kappa-BIB, TR-interacting protein 9, TRIP-9, ikB-B, ikB-beta, ikappaBbeta, nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta, thyroid receptor-interacting protein 9
- HostMouse
- IsotypeIgG1
- Protein IDQ15653
- Protein NameNF-kappa-B inhibitor beta
- Scientific DescriptionThe protein encoded by this gene belongs to the NF-kappa-B inhibitor family, which inhibit NF-kappa-B by complexing with, and trapping it in the cytoplasm. Phosphorylation of serine residues on these proteins by kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF-kappa-B, which translocates to the nucleus to function as a transcription factor. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Jul 2011]
- ReactivityHuman, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Arellano Buendia AS, Juárez Rojas JG, García-Arroyo F, et al. Antioxidant and anti-inflammatory effects of allicin in the kidney of an experimental model of metabolic syndrome. PeerJ. 2023,11:e16132. doi: 10.7717/peerj.16132Read this paper
- Hsueh YS, Chang HH, Shan YS, et al. Nuclear KIT induces a NFKBIB-RELA-KIT autoregulatory loop in imatinib-resistant gastrointestinal stromal tumors. Oncogene. 2019,38(38):6550-6565. doi: 10.1038/s41388-019-0900-9Read this paper
- Arellano Buendía AS, Tostado González M, Sánchez Reyes O, et al. Immunomodulatory Effects of the Nutraceutical Garlic Derivative Allicin in the Progression of Diabetic Nephropathy. Int J Mol Sci. 2018,19(10). doi: 10.3390/ijms19103107Read this paper








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