
Western blot analysis of IKK- alpha /IKK- beta phosphorylation expression in TNF treated NIH-3T3 whole cell lysates,The lane on the left is treated with the antigen-specific peptide.
IKK alpha (phospho Ser176) + IKK beta (phospho Ser177) antibody
GTX52310
ApplicationsWestern Blot, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetCHUK
Overview
- SupplierGeneTex
- Product NameIKK alpha (phospho Ser176) + IKK beta (phospho Ser177) antibody
- Delivery Days Customer9
- Antibody SpecificityCHUK
- Application Supplier NoteWB 1:500-1:2000, IHC 1:50-1:200
- ApplicationsWestern Blot, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID1147
- Target nameCHUK
- Target descriptioncomponent of inhibitor of nuclear factor kappa B kinase complex
- Target synonymsBPS2; conserved helix-loop-helix ubiquitous kinase; I-kappa-B kinase 1; I-kappa-B kinase-alpha; IkB kinase alpha subunit; IKBKA; IKK1; IKKA; IKK-a kinase; IKK-alpha; inhibitor of nuclear factor kappa-B kinase subunit alpha; NFKBIKA; Nuclear factor NFkappaB inhibitor kinase alpha; TCF16; TCF-16; transcription factor 16
- HostRabbit
- IsotypeIgG
- Protein IDO15111
- Protein NameInhibitor of nuclear factor kappa-B kinase subunit alpha
- Scientific DescriptionThis gene encodes a member of the serine/threonine protein kinase family. The encoded protein, a component of a cytokine-activated protein complex that is an inhibitor of the essential transcription factor NF-kappa-B complex, phosphorylates sites that trigger the degradation of the inhibitor via the ubiquination pathway, thereby activating the transcription factor. [provided by RefSeq, Jul 2008]
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Cacalol Acetate, a Sesquiterpene from Psacalium decompositum, Exerts an Anti-inflammatory Effect through LPS/NF-KB Signaling in Raw 264.7 Macrophages. Mora-Ramiro B et al., 2020 Aug 28, J Nat ProdRead more
- CXCL1/CXCR2 Paracrine Axis Contributes to Lung Metastasis in Osteosarcoma. Chao CC et al., 2020 Feb 17, Cancers (Basel)Read more
- Au Clusters Treat Rheumatoid Arthritis with Uniquely Reversing Cartilage/Bone Destruction. Gao F et al., 2019 Apr 3, Adv Sci (Weinh)Read more