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Western blot analysis of IKK- alpha /IKK- beta phosphorylation expression in TNF treated NIH-3T3 whole cell lysates,The lane on the left is treated with the antigen-specific peptide.
Western blot analysis of IKK- alpha /IKK- beta phosphorylation expression in TNF treated NIH-3T3 whole cell lysates,The lane on the left is treated with the antigen-specific peptide.
Western blot analysis of IKK- alpha /IKK- beta phosphorylation expression in TNF treated NIH-3T3 whole cell lysates,The lane on the left is treated with the antigen-specific peptide.

IKK alpha (phospho Ser176) + IKK beta (phospho Ser177) antibody

GTX52310
GeneTex
ApplicationsWestern Blot, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetCHUK
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Overview

  • Supplier
    GeneTex
  • Product Name
    IKK alpha (phospho Ser176) + IKK beta (phospho Ser177) antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB 1:500-1:2000, IHC 1:50-1:200
  • Applications
    Western Blot, ImmunoHistoChemistry
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID1147
  • Target name
    CHUK
  • Target description
    component of inhibitor of nuclear factor kappa B kinase complex
  • Target synonyms
    BPS2, IKBKA, IKK-1, IKK-alpha, IKK1, IKKA, NFKBIKA, TCF16, inhibitor of nuclear factor kappa-B kinase subunit alpha, I-kappa-B kinase 1, I-kappa-B kinase-alpha, IKK-a kinase, IkB kinase alpha subunit, Nuclear factor NFkappaB inhibitor kinase alpha, conserved helix-loop-helix ubiquitous kinase, transcription factor 16
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDO15111
  • Protein Name
    Inhibitor of nuclear factor kappa-B kinase subunit alpha
  • Scientific Description
    This gene encodes a member of the serine/threonine protein kinase family. The encoded protein, a component of a cytokine-activated protein complex that is an inhibitor of the essential transcription factor NF-kappa-B complex, phosphorylates sites that trigger the degradation of the inhibitor via the ubiquination pathway, thereby activating the transcription factor. [provided by RefSeq, Jul 2008]
  • Reactivity
    Human, Mouse, Rat
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Mora-Ramiro B, Jiménez-Estrada M, Zentella-Dehesa A, et al. Cacalol Acetate, a Sesquiterpene from Psacalium decompositum, Exerts an Anti-inflammatory Effect through LPS/NF-KB Signaling in Raw 264.7 Macrophages. J Nat Prod. 2020,83(8):2447-2455. doi: 10.1021/acs.jnatprod.0c00300
    Read this paper
  • Chao CC, Lee CW, Chang TM, et al. CXCL1/CXCR2 Paracrine Axis Contributes to Lung Metastasis in Osteosarcoma. Cancers (Basel). 2020,12(2). doi: 10.3390/cancers12020459
    Read this paper
  • Gao F, Yuan Q, Cai P, et al. Au Clusters Treat Rheumatoid Arthritis with Uniquely Reversing Cartilage/Bone Destruction. Adv Sci (Weinh). 2019,6(7):1801671. doi: 10.1002/advs.201801671
    Read this paper