
Western blot analysis of IKK- alpha /IKK- beta phosphorylation expression in TNF treated NIH-3T3 whole cell lysates,The lane on the left is treated with the antigen-specific peptide.
IKK alpha (phospho Ser176) + IKK beta (phospho Ser177) antibody
GTX52310
ApplicationsWestern Blot, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetCHUK
Overview
- SupplierGeneTex
- Product NameIKK alpha (phospho Ser176) + IKK beta (phospho Ser177) antibody
- Delivery Days Customer9
- Application Supplier NoteWB 1:500-1:2000, IHC 1:50-1:200
- ApplicationsWestern Blot, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID1147
- Target nameCHUK
- Target descriptioncomponent of inhibitor of nuclear factor kappa B kinase complex
- Target synonymsBPS2, IKBKA, IKK-1, IKK-alpha, IKK1, IKKA, NFKBIKA, TCF16, inhibitor of nuclear factor kappa-B kinase subunit alpha, I-kappa-B kinase 1, I-kappa-B kinase-alpha, IKK-a kinase, IkB kinase alpha subunit, Nuclear factor NFkappaB inhibitor kinase alpha, conserved helix-loop-helix ubiquitous kinase, transcription factor 16
- HostRabbit
- IsotypeIgG
- Protein IDO15111
- Protein NameInhibitor of nuclear factor kappa-B kinase subunit alpha
- Scientific DescriptionThis gene encodes a member of the serine/threonine protein kinase family. The encoded protein, a component of a cytokine-activated protein complex that is an inhibitor of the essential transcription factor NF-kappa-B complex, phosphorylates sites that trigger the degradation of the inhibitor via the ubiquination pathway, thereby activating the transcription factor. [provided by RefSeq, Jul 2008]
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Mora-Ramiro B, Jiménez-Estrada M, Zentella-Dehesa A, et al. Cacalol Acetate, a Sesquiterpene from Psacalium decompositum, Exerts an Anti-inflammatory Effect through LPS/NF-KB Signaling in Raw 264.7 Macrophages. J Nat Prod. 2020,83(8):2447-2455. doi: 10.1021/acs.jnatprod.0c00300Read this paper
- Chao CC, Lee CW, Chang TM, et al. CXCL1/CXCR2 Paracrine Axis Contributes to Lung Metastasis in Osteosarcoma. Cancers (Basel). 2020,12(2). doi: 10.3390/cancers12020459Read this paper
- Gao F, Yuan Q, Cai P, et al. Au Clusters Treat Rheumatoid Arthritis with Uniquely Reversing Cartilage/Bone Destruction. Adv Sci (Weinh). 2019,6(7):1801671. doi: 10.1002/advs.201801671Read this paper








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