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IL-1beta (human) (rec.) (His)

Research Use Only
CHI-HR-20001B
Chimerigen Laboratories
Product group Proteins / Signaling Molecules
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Overview

  • Supplier
    Chimerigen Laboratories
  • Product Name
    IL-1beta (human) (rec.) (His)
  • Delivery Days Customer
    10
  • Certification
    Research Use Only
  • Estimated Purity
    >98%
  • Scientific Description
    IL-1beta is produced by activated macrophages. IL-1beta stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1beta belongs to the IL-1 family of proteins that are involved in the inflammatory response. IL-1beta in most situations requires the inflammasome complex to be cleaved and secreted. - Protein. Human IL-1beta (aa 117-269) is fused at the C-terminus to a His-tag. Source: E. coli. Endotoxin content: <0.1EU/microg protein (LAL test; Lonza). Lyophilized from a concentrated sterile solution containing 50mM Tris-Hcl buffer (pH 8.0) and 100mM NaCl. Purity: >98% (SDS-PAGE). IL-1beta is produced by activated macrophages. IL-1beta stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1beta belongs to the IL-1 family of proteins that are involved in the inflammatory response. IL-1beta in most situations requires the inflammasome complex to be cleaved and secreted.
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352202