IL-36 alpha/IL-1F6, Human

MedChem Express

IL-36 alpha/IL-1F6, Human

10

Research Use Only

95.70

IL36A

interleukin 36 alpha

FIL1, FIL1(EPSILON), FIL1E, IL-1F6, IL1(EPSILON), IL1F6, interleukin-36 alpha, FIL1 epsilon, IL-1 epsilon, IL-1F6 (FIL-1-epsilon), interleukin 1 family, member 6 (epsilon), interleukin-1 epsilon, interleukin-1 family member 6

Interleukin-36 alpha

IL-36 alpha (IL-1F6), a subform of IL-36 family, belongs to IL-1 superfamily. IL-36 alpha mediates inflammatory response. IL-36 alpha binds to IL-36R and activates NF-kappaB and MAPK signaling pathways, but the activation requires N-terminal cleavage by neutrophil granule-derived proteases[1]. IL-36 alpha also binds to IL-1Rrp2 and recruit IL-1RAcP. IL-36 alpha activats the MAPK, Erk1/2 and JNK through IL-36R/IL-1RAcP[2]. IL-36 alpha/IL-1F6 Protein, Human is a recombinant human IL-36 alpha without any tag, which is produced in E. coli.

-20°C

41116100