IL1 beta antibody
GTX100793
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetIL1B
Overview
- SupplierGeneTex
- Product NameIL1 beta antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID3553
- Target nameIL1B
- Target descriptioninterleukin 1 beta
- Target synonymsIL-1, IL1-BETA, IL1F2, IL1beta, interleukin-1 beta, IL-1 beta, catabolin, interleukin 1beta, preinterleukin 1 beta, pro-interleukin-1-beta
- HostRabbit
- IsotypeIgG
- Protein IDP01584
- Protein NameInterleukin-1 beta
- Scientific DescriptionThe protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. [provided by RefSeq]
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Zhang C, Chen M, Chi Z. Cytokine secretion and pyroptosis of cholesteatoma keratinocytes mediated by AIM2 inflammasomes in response to cytoplasmic DNA. Mol Med Rep. 2021,23(5):pii: 344. doi: 10.3892/mmr.2021.11983.Read this paper

![Sandwich ELISA analysis of serial diluted human IL-1b recombinant protein(50ul per well) using IL1 beta antibody [ILB1-H6] Coating : GTX15756 IL1 beta antibody [ILB1-H67](5 microg/mL) Detection : GTX15755 IL1 beta antibody [ILB1-H6] (Biotin) (0.07 microg/mL)](https://www.genetex.com/upload/website/prouct_img/normal/GTX15755/GTX15755_58_ELISA_w_23060620_191.webp)
![Sandwich ELISA analysis of serial diluted human IL-1b recombinant protein(50ul per well) using IL1 beta antibody [ILB1-H6] Coating : GTX15756 IL1 beta antibody [ILB1-H67](5 microg/mL) Detection : GTX15755 IL1 beta antibody [ILB1-H6] (Biotin) (0.07 microg/mL)](https://www.genetex.com/upload/website/prouct_img/normal/GTX15756/GTX15756_59_ELISA_w_23060620_736.webp)

![ELISA analysis of antigen using GTX60513 IL1 beta antibody [3A6]. Black : Control antigen 100ng Purple : Antigen 10ng Blue : Antigen 50ng Red : Antigen 100ng](https://www.genetex.com/upload/website/prouct_img/normal/GTX60513/GTX60513_20170912_ELISA_w_23061123_881.webp)