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IL1 beta antibody

GTX130021
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry
DownloadDatasheet
Product group Antibodies
ReactivityHuman
TargetIL1B
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Overview

  • Supplier
    GeneTex
  • Product Name
    IL1 beta antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1.13 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID3553
  • Target name
    IL1B
  • Target description
    interleukin 1 beta
  • Target synonyms
    catabolin; IL-1; IL-1 beta; IL1beta; IL1-BETA; IL1F2; interleukin 1beta; interleukin-1 beta; preinterleukin 1 beta; pro-interleukin-1-beta
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP01584
  • Protein Name
    Interleukin-1 beta
  • Scientific Description
    The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. [provided by RefSeq]
  • Reactivity
    Human
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Inhibition of AIM2 inflammasome activation by SOX/ORF37 promotes lytic replication of Kaposis sarcoma-associated herpesvirus.
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  • Zika Virus Infection Induces Interleukin-1beta-Mediated Inflammatory Responses by Macrophages in the Brain of an Adult Mouse Model.
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  • Small-molecule PIK-93 modulates the tumor microenvironment to improve immune checkpoint blockade response.
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  • Discrepant Activation Pattern of Inflammation and Pyroptosis Induced in Dermal Fibroblasts in Response to Dengue Virus Serotypes 1 and 2 and Nonstructural Protein 1.
    Read more
  • miR-let-7c-5p and miR-149-5p inhibit proinflammatory cytokine production in osteoarthritis and rheumatoid arthritis synovial fibroblasts. Law YY et al., 2021 Jul 1, Aging (Albany NY)
    Read more
  • Ischemic Stroke Risk Associated with Mitochondrial Haplogroup F in the Asian Population. Tsai MH et al., 2020 Aug 11, Cells
    Read more
  • Ascorbic Acid Mitigates D-galactose-Induced Brain Aging by Increasing Hippocampal Neurogenesis and Improving Memory Function. Nam SM et al., 2019 Jan 15, Nutrients
    Read more