Overview
- SupplierGeneTex
- Product NameIL1 beta antibody
- Delivery Days Customer9
- CertificationResearch Use Only
- Concentration1.20 mg/ml
- IsotypeIgG
- Scientific DescriptionThe protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. [provided by RefSeq]
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203
References
- Ascorbic Acid Mitigates D-galactose-Induced Brain Aging by Increasing Hippocampal Neurogenesis and Improving Memory Function. Nam SM et al., 2019 Jan 15, NutrientsRead more
- Ischemic Stroke Risk Associated with Mitochondrial Haplogroup F in the Asian Population. Tsai MH et al., 2020 Aug 11, CellsRead more
- Ischemic Stroke Risk Associated with Mitochondrial Haplogroup F in the Asian Population. Tsai MH et al., 2020 Aug 11, CellsRead more
- miR-let-7c-5p and miR-149-5p inhibit proinflammatory cytokine production in osteoarthritis and rheumatoid arthritis synovial fibroblasts. Law YY et al., 2021 Jul 1, Aging (Albany NY)Read more