IL1 beta antibody

GeneTex

IL1 beta antibody

9

The antibody will neutralize the biological activity of recombinant mouse IL-1β, but not recombinant human IL-1β. The antibody shows ~25% cross-reactivity with recombinant human IL-1β.,We do not recommend use of this product for Human.

WB: 1-2 microg/ml. Neutralizing/Inhibition: 50 pg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot, Neutralisation/Blocking

Research Use Only

Polyclonal

Unconjugated

Il1b

interleukin 1 beta

IL-; IL-1 beta; Il-1b; IL-1beta; interleukin-1 beta

Goat

IgG

Interleukin-1 beta

The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. [provided by RefSeq, Jul 2008]

Mouse

-20°C or -80°C,2°C to 8°C

12352203