
WB analysis of mouse liver tissue lysate using GTX55675 IL1 beta antibody. Dilution : 1:1000 Loading : 25microg per lane
IL1 beta antibody
GTX55675
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityBovine, Human, Mouse, Rat
TargetIL1B
Overview
- SupplierGeneTex
- Product NameIL1 beta antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500 - 1:2000. ICC/IF: 1:50 - 1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID3553
- Target nameIL1B
- Target descriptioninterleukin 1 beta
- Target synonymscatabolin; IL-1; IL-1 beta; IL1beta; IL1-BETA; IL1F2; interleukin 1beta; interleukin-1 beta; preinterleukin 1 beta; pro-interleukin-1-beta
- HostRabbit
- IsotypeIgG
- Protein IDP01584
- Protein NameInterleukin-1 beta
- Scientific DescriptionThe protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. [provided by RefSeq, Jul 2008]
- ReactivityBovine, Human, Mouse, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Biejiajian Pill Ameliorates Diabetes-Associated Atherosclerosis through Inhibition of the NLRP3 Inflammasome. Fu Y et al., 2022, Evid Based Complement Alternat MedRead more
- Staphylococcus aureus mediates pyroptosis in bovine mammary epithelial cell via activation of NLRP3 inflammasome. Wang X et al., 2022 Feb 5, Vet ResRead more
- Surfactant effects on the viability and function of human mesenchymal stem cells: in vitro and in vivo assessment. Chen CM et al., 2017 Aug 3, Stem Cell Res TherRead more