Sandwich ELISA analysis of human IL-10 protein using GTX02950 IL10 antibody [9D7] as coating antibody and GTX02948-02 IL10 antibody [12G8] (Biotin) as detecting antibody. Substrate : pNPP
Sandwich ELISA analysis of human IL-10 protein using GTX02950 IL10 antibody [9D7] as coating antibody and GTX02948-02 IL10 antibody [12G8] (Biotin) as detecting antibody. Substrate : pNPP
IL10 antibody [12G8] (Biotin)
GTX02948-02
Overview
- SupplierGeneTex
- Product NameIL10 antibody [12G8] (Biotin)
- Delivery Days Customer9
- Antibody SpecificityThis antibody is able to detect native and recombinant human IL-10.
- Application Supplier Note*Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsELISA
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone ID12G8
- Concentration1 mg/ml
- ConjugateBiotin
- FormulationLiquid
- Gene ID3586
- Target nameIL10
- Target descriptioninterleukin 10
- Target synonymsCSIF; cytokine synthesis inhibitory factor; GVHDS; IL-10; IL10A; interleukin-10; T-cell growth inhibitory factor; TGIF
- HostRat
- IsotypeIgG2a
- Protein IDP22301
- Protein NameInterleukin-10
- Scientific DescriptionThe protein encoded by this gene is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract. Mutations in this gene are associated with an increased susceptibility to HIV-1 infection and rheumatoid arthritis.[provided by RefSeq, May 2011]
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203