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ProductsBack/IL10 antibody [JES5-2A5]

IL10 antibody [JES5-2A5]

GTX27379

ApplicationsWestern Blot, ELISA

Product group Antibodies

TargetIl10

Overview

Supplier
GeneTex
Product Name
IL10 antibody [JES5-2A5]
Delivery Days Customer
9
Applications
Western Blot, ELISA
Certification
Research Use Only
Clonality
Monoclonal
Clone ID
JES5-2A5
Concentration
0.5 mg/ml
Conjugate
Unconjugated
Gene ID16153
Target name
Il10
Target description
interleukin 10
Target synonyms
CSIF, If2a, Il-10, interleukin-10, cytokine synthesis inhibitory factor, interferon 2a
Host
Rat
Isotype
IgG2
Protein IDP18893
Protein Name
Interleukin-10
Scientific Description
This gene encodes an anti-inflammatory cytokine that is a member of the class-2 cytokine family. The encoded protein is secreted by cells of both the innate and adaptive immune systems and is crucial for limiting the immune response to a broad range of pathogens. It also has been shown to suppress autoimmune responses. This protein mediates its immunosuppressive signal through a specific interleukin 10 receptor complex. Aberrant functioning of this gene is associated with numerous immune disorders including graft-versus-host disease, and increased susceptibility to HIV-1 infection and rheumatoid arthritis. [provided by RefSeq, Sep 2015]
Storage Instruction
2°C to 8°C
UNSPSC
12352203

References

Minshawi F, Lanvermann S, McKenzie E, et al. The Generation of an Engineered Interleukin-10 Protein With Improved Stability and Biological Function. Front Immunol. 2020,11:1794. doi: 10.3389/fimmu.2020.01794
Read this paper
Salmon RA, Guo X, Teh HS, et al. The p38 mitogen-activated protein kinases can have opposing roles in the antigen-dependent or endotoxin-stimulated production of IL-12 and IFN-gamma. Eur J Immunol. 2001,31(11):3218-27.
Read this paper

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