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IL10 Receptor alpha antibody

GTX102731
GeneTex
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetIL10RA
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Overview

  • Supplier
    GeneTex
  • Product Name
    IL10 Receptor alpha antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1.68 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID3587
  • Target name
    IL10RA
  • Target description
    interleukin 10 receptor subunit alpha
  • Target synonyms
    CD210; CD210a; CDW210A; HIL-10R; IL-10 receptor subunit alpha; IL10R; IL-10R subunit 1; IL-10R subunit alpha; IL-10R1; IL-10RA; interleukin 10 receptor, alpha; interleukin-10 receptor alpha chain; interleukin-10 receptor subunit 1; interleukin-10 receptor subunit alpha
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ13651
  • Protein Name
    Interleukin-10 receptor subunit alpha
  • Scientific Description
    The protein encoded by this gene is a receptor for interleukin 10. This protein is structurally related to interferon receptors. It has been shown to mediate the immunosuppressive signal of interleukin 10, and thus inhibits the synthesis of proinflammatory cytokines. This receptor is reported to promote survival of progenitor myeloid cells through the insulin receptor substrate-2/PI 3-kinase/AKT pathway. Activation of this receptor leads to tyrosine phosphorylation of JAK1 and TYK2 kinases. Two transcript variants, one protein-coding and the other not protein-coding, have been found for this gene. [provided by RefSeq]
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • A Fucoxanthinol Induces Apoptosis in a Pancreatic Intraepithelial Neoplasia Cell. Terasaki M et al., 2021 Mar-Apr, Cancer Genomics Proteomics
    Read more
  • IL10 inhibits starvation-induced autophagy in hypertrophic scar fibroblasts via cross talk between the IL10-IL10R-STAT3 and IL10-AKT-mTOR pathways. Shi J et al., 2016 Mar 10, Cell Death Dis
    Read more

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