IL10RA Polyclonal Antibody

Elabscience

IL10RA Polyclonal Antibody

12

ImmunoHistoChemistry

ELISA IHC

Research Use Only

Polyclonal

0.6 mg/ml

Unconjugated

IL10RA

interleukin 10 receptor subunit alpha

CD210, CD210a, CDW210A, HIL-10R, IL-10R1, IL10R, interleukin-10 receptor subunit alpha, IL-10 receptor subunit alpha, IL-10R subunit 1, IL-10R subunit alpha, interleukin 10 receptor, alpha, interleukin-10 receptor alpha chain, interleukin-10 receptor subunit 1

Rabbit

IgG

Interleukin-10 receptor subunit alpha

The protein encoded by this gene is a receptor for interleukin 10. This protein is structurally related to interferon receptors. It has been shown to mediate the immunosuppressive signal of interleukin 10, and thus inhibits the synthesis of proinflammatory cytokines. This receptor is reported to promote survival of progenitor myeloid cells through the insulin receptor substrate-2/PI 3-kinase/AKT pathway. Activation of this receptor leads to tyrosine phosphorylation of JAK1 and TYK2 kinases. Two transcript variants, one protein-coding and the other not protein-coding, have been found for this gene.

-20°C

41116161