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IL12 antibody

GTX20050
GeneTex
ApplicationsELISA, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, RadioImmunoAssay
Product group Antibodies
TargetIL12B
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Overview

  • Supplier
    GeneTex
  • Product Name
    IL12 antibody [1-1A4]
  • Delivery Days Customer
    9
  • Application Supplier Note
    For ELISA: Use at an assay dependent concentration. For RIA: Use at an assay dependent concentration. Optimal dilutions/concentrations should be determined by the end user.
  • Applications
    ELISA, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, RadioImmunoAssay
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Concentration
    0.7 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID3593
  • Target name
    IL12B
  • Target description
    interleukin 12B
  • Target synonyms
    CLMF, CLMF2, IL-12B, IMD28, IMD29, NKSF, NKSF2, interleukin-12 subunit beta, CLMF p40, IL-12 subunit p40, IL12, subunit p40, NK cell stimulatory factor chain 2, cytotoxic lymphocyte maturation factor 40 kDa subunit, interleukin 12, p40, interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40), interleukin-12 beta chain, natural killer cell stimulatory factor, 40 kD subunit
  • Host
    Mouse
  • Isotype
    IgG1
  • Scientific Description
    IL12 is a heterodimeric cytokine comprised of p35 and p40 subunits. IL12 plays a central role in mediating cell mediated immunity, promoting differentiation of CD4+ T cells to the Th1 subset and of CD8+ T cells into mature cytotoxic T lymphocytes (CTLs). IL12 is a potent stimulator of NK cells. IL12 therapy has been suggested as a method of enhancing cytocidal anti tumour immune responses.
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • An unrestrained proinflammatory M1 macrophage population induced by iron impairs wound healing in humans and mice. Sindrilaru A et al., 2011 Mar, J Clin Invest
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