IL12 antibody

GeneTex

IL12 antibody [1-1A4]

9

Recognises p35/40 heterodimer and p40. Used against CCHO and Baculovirus derived recombinant IL-12. Reacts with stimulated and unstimulated monocytes.

For ELISA: Use at an assay dependent concentration. For RIA: Use at an assay dependent concentration. Optimal dilutions/concentrations should be determined by the end user.

ELISA, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, RadioImmunoAssay

Research Use Only

Monoclonal

0.7 mg/ml

Unconjugated

IL12B

interleukin 12B

CLMF; CLMF p40; CLMF2; cytotoxic lymphocyte maturation factor 40 kDa subunit; IL-12 subunit p40; IL12, subunit p40; IL-12B; IMD28; IMD29; interleukin 12, p40; interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40); interleukin-12 beta chain; interleukin-12 subunit beta; natural killer cell stimulatory factor, 40 kD subunit; NK cell stimulatory factor chain 2; NKSF; NKSF2

Mouse

IgG1

IL12 is a heterodimeric cytokine comprised of p35 and p40 subunits. IL12 plays a central role in mediating cell mediated immunity, promoting differentiation of CD4+ T cells to the Th1 subset and of CD8+ T cells into mature cytotoxic T lymphocytes (CTLs). IL12 is a potent stimulator of NK cells. IL12 therapy has been suggested as a method of enhancing cytocidal anti tumour immune responses.

Human

-20°C or -80°C,2°C to 8°C

12352203