IL13 Antibody - C-terminal region

Aviva Systems Biology

IL13 Antibody - C-terminal region

23

WB: 1:1000 IF: 1:10~50 IHC-P: 1:10~50

ImmunoFluorescence, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Polyclonal

0.4 mg/ml

Liquid. PBS with 0.09% (W/V) sodium azide.

IL13

interleukin 13

IL-13, P600, interleukin-13

Rabbit

Interleukin-13

This gene encodes an immunoregulatory cytokine produced primarily by activated Th2 cells. This cytokine is involved in several stages of B-cell maturation and differentiation. It up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. This cytokine down-regulates macrophage activity, thereby inhibits the production of pro-inflammatory cytokines and chemokines. This cytokine is found to be critical to the pathogenesis of allergen-induced asthma but operates through mechanisms independent of IgE and eosinophils. This gene, IL3, IL5, IL4, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL4.

Human

-20°C,2°C to 8°C

41116161