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IL17A antibody

GTX133781
GeneTex
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetIL17A
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Overview

  • Supplier
    GeneTex
  • Product Name
    IL17A antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1.15 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID3605
  • Target name
    IL17A
  • Target description
    interleukin 17A
  • Target synonyms
    CTLA-8, CTLA8, IL-17, IL-17A, IL17, ILA17, interleukin-17A, cytotoxic T-lymphocyte-associated antigen 8, cytotoxic T-lymphocyte-associated protein 8, interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8), interleukin-17
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ16552
  • Protein Name
    Interleukin-17A
  • Scientific Description
    The protein encoded by this gene is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis. [provided by RefSeq]
  • Reactivity
    Human, Mouse, Rat
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Peng HY, Chen SY, Siao SH, et al. Targeting a cysteine protease from a pathobiont alleviates experimental arthritis. Arthritis Res Ther. 2020,22(1):114. doi: 10.1186/s13075-020-02205-z
    Read this paper