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WB analysis of THP-1 cells treated by PMA (80 nM) at 37oC for overnight using GTX32674 IL17A antibody. The signal was developed with ECL plus-Enhanced. Dilution : 1:1000 Loading : 25microg per lane
WB analysis of THP-1 cells treated by PMA (80 nM) at 37oC for overnight using GTX32674 IL17A antibody. The signal was developed with ECL plus-Enhanced. Dilution : 1:1000 Loading : 25microg per lane
WB analysis of THP-1 cells treated by PMA (80 nM) at 37oC for overnight using GTX32674 IL17A antibody. The signal was developed with ECL plus-Enhanced. Dilution : 1:1000 Loading : 25microg per lane

IL17A antibody

GTX32674
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen
DownloadDatasheet
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetIL17A
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Overview

  • Supplier
    GeneTex
  • Product Name
    IL17A antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500 - 1:2000. ICC/IF: 1:50 - 1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Conjugate
    Unconjugated
  • Gene ID3605
  • Target name
    IL17A
  • Target description
    interleukin 17A
  • Target synonyms
    CTLA8; CTLA-8; cytotoxic T-lymphocyte-associated antigen 8; cytotoxic T-lymphocyte-associated protein 8; IL17; IL-17; IL-17A; ILA17; interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8); interleukin-17; interleukin-17A
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ16552
  • Protein Name
    Interleukin-17A
  • Scientific Description
    The protein encoded by this gene is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis. [provided by RefSeq, Jul 2008]
  • Reactivity
    Human, Mouse, Rat
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Secukinumab attenuates reactive astrogliosis via IL-17RA/(C/EBPbeta)/SIRT1 pathway in a rat model of germinal matrix hemorrhage. Liu SP et al., 2019 Oct, CNS Neurosci Ther
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