IL17A antibody

Biorbyt

IL17A antibody

16

Western Blot, ELISA

WB 1:500 - 1:2000, IF/ 1:50 - 1:200 ELISA, WB

Research Use Only

Polyclonal

Unconjugated

IL17A

interleukin 17A

CTLA-8, CTLA8, IL-17, IL-17A, IL17, ILA17, interleukin-17A, cytotoxic T-lymphocyte-associated antigen 8, cytotoxic T-lymphocyte-associated protein 8, interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8), interleukin-17

Rabbit

IgG

Interleukin-17A

Rabbit polyclonal to IL17A.IL-17A is a cystine-linked homodimeric pro-inflammatory cytokine produced by Th17 cells, a distinct CD4+ T cell lineage. IL-17A stimulates the production of the pro-inflammatory cytokines IL-1beta, TNF-alpha, and IL-6. IL-17A also induces production of the neutrophil chemoattractants IL-8, CXCL1, and CXCL6 thereby bridging adaptive and innate immunity. IL-17A is intimately involved in mucosal immunity against bacterial infections and has a putative role in some autoimmune disorders. IL-17A effects appear to be exerted primarily through binding to the IL-17RA. IL-17A binding induces production of cytokines, chemokines and other proteins through activation of the Erk1/2 MAP kinase, PI3K/Akt, p38, and NF-kB pathways.

Human

-20°C,2°C to 8°C

12352203