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ProductsBack/IL2 Receptor alpha antibody [BC96]

IL2 Receptor alpha antibody [BC96]

Research Use Only
GTX01471
GeneTex
ApplicationsFlow Cytometry
DownloadDatasheet
Product group Antibodies
ReactivityHuman, Monkey, Primate
TargetIL2RA
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More than 130 suppliers
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Overview

  • Supplier
    GeneTex
  • Product Name
    IL2 Receptor alpha antibody [BC96]
  • Delivery Days Customer
    9
  • Applications
    Flow Cytometry
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    BC96
  • Concentration
    0.5 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID3559
  • Target name
    IL2RA
  • Target description
    interleukin 2 receptor subunit alpha
  • Target synonyms
    CD25; IDDM10; IL-2 receptor subunit alpha; IL2R; IL-2R subunit alpha; IMD41; interleukin 2 receptor, alpha; interleukin-2 receptor subunit alpha; p55; TAC antigen; TCGFR
  • Host
    Mouse
  • Isotype
    IgG1
  • Scientific Description
    The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. Alternately-spliced IL2RA mRNAs have been isolated, but the significance of each is presently unknown. Mutations in this gene are associated with interleukin 2 receptor alpha deficiency.[provided by RefSeq, Nov 2009]
  • Reactivity
    Human, Monkey, Primate
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203

References

  • Experimental infection of Cynomolgus Macaques (Macaca fascicularis) with human varicella-zoster virus. Willer DO et al., 2012 Apr, J Virol
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  • IL-1beta and TNFalpha-initiated IL-6-STAT3 pathway is critical in mediating inflammatory cytokines and RANKL expression in inflammatory arthritis. Mori T et al., 2011 Nov, Int Immunol
    Read more
  • Leukocyte composition of human breast cancer. Ruffell B et al., 2012 Feb 21, Proc Natl Acad Sci U S A
    Read more
  • Cytokine signals through PI-3 kinase pathway modulate Th17 cytokine production by CCR6+ human memory T cells. Wan Q et al., 2011 Aug 29, J Exp Med
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  • Human cord blood CD4+CD25hi regulatory T cells suppress prenatally acquired T cell responses to Plasmodium falciparum antigens. Mackroth MS et al., 2011 Mar 1, J Immunol
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  • Antiviral therapy during primary simian immunodeficiency virus infection fails to prevent acute loss of CD4+ T cells in gut mucosa but enhances their rapid restoration through central memory T cells. Verhoeven D et al., 2008 Apr, J Virol
    Read more