FACS analysis of human PBMC cells using GTX18275 IL2 Receptor alpha antibody [MEM-181] (FITC). The mononuclear cells were isolated from human peripheral blood, devided in aliquots for duplicate analysis and stimulated with PHA for 2 days. Panel A, C : staining with GTX18275 Panel B, D : staining with a positive control anti-CD25 monoclonal antibody
IL2 Receptor alpha antibody [MEM-181] (FITC)
GTX18275
Overview
- SupplierGeneTex
- Product NameIL2 Receptor alpha antibody [MEM-181] (FITC)
- Delivery Days Customer9
- Application Supplier NoteFACS: 20 microl reagent / 100 microl of whole blood or 106 cells in a suspension. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsFlow Cytometry
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDMEM-181
- ConjugateFITC
- FormulationLiquid
- Gene ID3559
- Target nameIL2RA
- Target descriptioninterleukin 2 receptor subunit alpha
- Target synonymsCD25; IDDM10; IL-2 receptor subunit alpha; IL2R; IL-2R subunit alpha; IMD41; interleukin 2 receptor, alpha; interleukin-2 receptor subunit alpha; p55; TAC antigen; TCGFR
- HostMouse
- IsotypeIgG1
- Protein IDP01589
- Protein NameInterleukin-2 receptor subunit alpha
- Scientific DescriptionThe interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. Alternately-spliced IL2RA mRNAs have been isolated, but the significance of each is presently unknown. Mutations in this gene are associated with interleukin 2 receptor alpha deficiency.[provided by RefSeq, Nov 2009]
- ReactivityHuman
- Storage Instruction2°C to 8°C
- UNSPSC12352203