ProductsBack/IL2 Receptor alpha antibody [PC61.5] (Biotin)

FACS analysis of mouse C57Bl/6 splenocytes using GTX01472-02 IL2 Receptor alpha antibody [PC61.5] (Biotin). Right panel : co-stained with IL2 Receptor alpha antibody [PC61.5] (Biotin) and Mouse CD4 antibody (APC) Left panel : co-stained with isotype control and Mouse CD4 antibody (APC) antibody amount : 0.125 microg (5 microl)

IL2 Receptor alpha antibody [PC61.5] (Biotin)

GTX01472-02

ApplicationsFlow Cytometry

Product group Antibodies

ReactivityMouse

TargetIl2ra

Overview

Supplier
GeneTex
Product Name
IL2 Receptor alpha antibody [PC61.5] (Biotin)
Delivery Days Customer
9
Application Supplier Note
*Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Applications
Flow Cytometry
Certification
Research Use Only
Clonality
Monoclonal
Clone ID
PC61.5
Concentration
0.5 mg/ml
Conjugate
Biotin
Gene ID16184
Target name
Il2ra
Target description
interleukin 2 receptor, alpha chain
Target synonyms
CD25, Il2r, Ly-43, interleukin-2 receptor subunit alpha, IL-2 receptor subunit alpha, IL-2-RA, IL-2R alpha chain, IL-2R subunit alpha, IL2-RA, p55 chain
Host
Rat
Isotype
IgG1
Protein IDP01590
Protein Name
Interleukin-2 receptor subunit alpha
Reactivity
Mouse
Storage Instruction
2°C to 8°C
UNSPSC
12352203

References

Lee LF, Logronio K, Tu GH, et al. Anti-IL-7 receptor-α reverses established type 1 diabetes in nonobese diabetic mice by modulating effector T-cell function. Proc Natl Acad Sci U S A. 2012,109(31):12674-9. doi: 10.1073/pnas.1203795109
Read this paper
Liang D, Zuo A, Shao H, et al. Role of CD25+ dendritic cells in the generation of Th17 autoreactive T cells in autoimmune experimental uveitis. J Immunol. 2012,188(11):5785-91. doi: 10.4049/jimmunol.1200109
Read this paper
Yu P, Steel JC, Zhang M, et al. Simultaneous inhibition of two regulatory T-cell subsets enhanced Interleukin-15 efficacy in a prostate tumor model. Proc Natl Acad Sci U S A. 2012,109(16):6187-92. doi: 10.1073/pnas.1203479109
Read this paper
Attridge K, Wang CJ, Wardzinski L, et al. IL-21 inhibits T cell IL-2 production and impairs Treg homeostasis. Blood. 2012,119(20):4656-64. doi: 10.1182/blood-2011-10-388546
Read this paper
Tang S, Moore ML, Grayson JM, et al. Increased CD8+ T-cell function following castration and immunization is countered by parallel expansion of regulatory T cells. Cancer Res. 2012,72(8):1975-85. doi: 10.1158/0008-5472.CAN-11-2499
Read this paper
Koehn BH, Ford ML, Ferrer IR, et al. PD-1-dependent mechanisms maintain peripheral tolerance of donor-reactive CD8+ T cells to transplanted tissue. J Immunol. 2008,181(8):5313-22.
Read this paper
Leithäuser F, Meinhardt-Krajina T, Fink K, et al. Foxp3-expressing CD103+ regulatory T cells accumulate in dendritic cell aggregates of the colonic mucosa in murine transfer colitis. Am J Pathol. 2006,168(6):1898-909.
Read this paper
Lowenthal JW, Zubler RH, Nabholz M, et al. Similarities between interleukin-2 receptor number and affinity on activated B and T lymphocytes. Nature. 1985,315(6021):669-72.
Read this paper
Ceredig R, Lowenthal JW, Nabholz M, et al. Expression of interleukin-2 receptors as a differentiation marker on intrathymic stem cells. Nature. 1985,314(6006):98-100.
Read this paper
Hashimoto N, Nabholz M, MacDonald HR, et al. Dissociation of interleukin 2-dependent and -independent B cell proliferation with monoclonal anti-interleukin 2 receptor antibody. Eur J Immunol. 1986,16(3):317-20.
Read this paper

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IL2 Receptor alpha antibody [PC61.5] (Biotin)

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Overview

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