IL2 Receptor alpha antibody [PC61.5]

Anti-IL-7 receptor-alpha reverses established type 1 diabetes in nonobese diabetic mice by modulating effector T-cell function. Lee LF et al., 2012 Jul 31, Proc Natl Acad Sci U S A

Role of CD25+ dendritic cells in the generation of Th17 autoreactive T cells in autoimmune experimental uveitis. Liang D et al., 2012 Jun 1, J Immunol

Simultaneous inhibition of two regulatory T-cell subsets enhanced Interleukin-15 efficacy in a prostate tumor model. Yu P et al., 2012 Apr 17, Proc Natl Acad Sci U S A

IL-21 inhibits T cell IL-2 production and impairs Treg homeostasis. Attridge K et al., 2012 May 17, Blood

Increased CD8+ T-cell function following castration and immunization is countered by parallel expansion of regulatory T cells. Tang S et al., 2012 Apr 15, Cancer Res

PD-1-dependent mechanisms maintain peripheral tolerance of donor-reactive CD8+ T cells to transplanted tissue. Koehn BH et al., 2008 Oct 15, J Immunol

Foxp3-expressing CD103+ regulatory T cells accumulate in dendritic cell aggregates of the colonic mucosa in murine transfer colitis. Leithaeuser F et al., 2006 Jun, Am J Pathol

Similarities between interleukin-2 receptor number and affinity on activated B and T lymphocytes. Lowenthal JW et al., 1985 Jun 20-26, Nature

Expression of interleukin-2 receptors as a differentiation marker on intrathymic stem cells. Ceredig R et al., 1985 Mar 7-13, Nature

Dissociation of interleukin 2-dependent and -independent B cell proliferation with monoclonal anti-interleukin 2 receptor antibody. Hashimoto N et al., 1986 Mar, Eur J Immunol