Bio-Connect

IL37 Polyclonal Antibody

Research Use Only
RD218110A
Reddot Biotech
ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetIL37
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Overview

  • Supplier
    Reddot Biotech
  • Product Name
    IL37 Polyclonal Antibody
  • Delivery Days Customer
    5
  • Applications
    Western Blot, ELISA, ImmunoHistoChemistry
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1.5 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID27178
  • Target name
    IL37
  • Target description
    interleukin 37
  • Target synonyms
    FIL1; FIL1 zeta; FIL1(ZETA); FIL1Z; IL-1 zeta; IL1F7; IL-1F7; IL1F7 (canonical product IL-1F7b); IL-1F7b (IL-1H4, IL-1H, IL-1RP1); IL-1H; IL1H4; IL-1H4; IL1RP1; IL-1RP1; IL-1X protein; IL-23; IL-37; interleukin 1 family member 7; interleukin 1, zeta; interleukin-1 homolog 4; interleukin-1 superfamily z; interleukin-1-related protein; interleukin-23; interleukin-37
  • Host
    Rabbit
  • Isotype
    IgG
  • Scientific Description
    The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine can bind to, and may be a ligand for interleukin 18 receptor (IL18R1/IL-1Rrp). This cytokine also binds to interleukin 18 binding protein (IL18BP), an inhibitory binding protein of interleukin 18 (IL18), and subsequently forms a complex with IL18 receptor beta subunit, and through which it inhibits the activity of IL18. This gene along with eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. Five alternatively spliced transcript variants encoding distinct isoforms have been reported. IL37 (Interleukin 37) is a Protein Coding gene. Diseases associated with IL37 include Rheumatoid Arthritis. Among its related pathways are Innate Immune System and Toll-Like receptor Signaling Pathways. GO annotations related to this gene include cytokine activity and interleukin-1 receptor binding. An important paralog of this gene is IL36G.
  • Reactivity
    Human
  • Storage Instruction
    -20°C
  • UNSPSC
    12352203