IL4R / CD124 Antibody (aa1-232, clone R401, Preservative Free)

LifeSpan BioSciences

IL4R / CD124 Antibody (aa1-232, clone R401, Preservative Free)

14

Human IL4R. No cross-reactivity with Mouse IL4R and Rat IL4R in ELISA assay

Block: In a functional ELISA, 1. 2 microg/ml of the Rabbit Anti-Human IL4R Monoclonal antibody will block 50% of the binding of 2 microg/ml of Human IL4 to immobilized Recombinant Human IL4R ) coated at 0.5 microg/ml (100 microL/well). At 5 ug/ml, this antibody will block >90% of the binding. Neutralization: The neutralization activity of IL4R Neutralizing Antibody is Measured by its ability to neutralize IL4 induced proliferation in the human erythroleukemia cell line (TF-1). The Neutralization titer (IC50) is typically 1-4 ng/mL in the presence of 0.2 ng/mL Recombinant Human IL4. Please Note: Optimal concentrations/dilutions should be determined by the end user.. Block (2 µg/ml), ELISA (1.2 µg/ml), Neut (0.2 ng/ml) Block: In a functional ELISA, 1. 2 µg/ml of the Rabbit Anti-Human IL4R Monoclonal antibody will block 50% of the binding of 2 µg/ml of Human IL4 to immobilized Recombinant Human IL4R ) coated at 0.5 µg/ml (100 µL/well). At 5 ug/ml, this antibody will block >90% of the binding. Neutralization: The neutralization activity of IL4R Neutralizing Antibody is Measured by its ability to neutralize IL4 induced proliferation in the human erythroleukemia cell line (TF-1). The Neutralization titer (IC50) is typically 1-4 ng/mL in the presence of 0.2 ng/mL Recombinant Human IL4. Please Note: Optimal concentrations/dilutions should be determined by the end user.

ELISA, Neutralisation/Blocking

Research Use Only

Monoclonal

R401

Unconjugated

...

IL4R

interleukin 4 receptor

CD124; IL-4 receptor subunit alpha; IL4R nirs variant 1; IL4RA; IL-4RA; interleukin 13 receptor; interleukin-4 receptor alpha chain; interleukin-4 receptor subunit alpha

Rabbit

IgG

Human

-20°C or -80°C,2°C to 8°C

12352203