IL7 antibody [M25]

GeneTex

IL7 antibody [M25]

9

The M25 antibody is useful for neutralizing the bioactivity of IL-7 as well as administration of IL-7 cytokine. IL-7 administration as a complex with M25 prolongs IL-7 availability in vivo by decreasing specific and nonspecific consumption.

*Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Neutralisation/Blocking, Other Application

Research Use Only

Monoclonal

M25

Unconjugated

IL7

interleukin 7

IL-7; interleukin-7

Mouse

IgG2b

Interleukin-7

The protein encoded by this gene is a cytokine important for B and T cell development. This cytokine and the hepatocyte growth factor (HGF) form a heterodimer that functions as a pre-pro-B cell growth-stimulating factor. This cytokine is found to be a cofactor for V(D)J rearrangement of the T cell receptor beta (TCRB) during early T cell development. This cytokine can be produced locally by intestinal epithelial and epithelial goblet cells, and may serve as a regulatory factor for intestinal mucosal lymphocytes. Knockout studies in mice suggested that this cytokine plays an essential role in lymphoid cell survival. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional splice variants have been described but their presence in normal tissues has not been confirmed.[provided by RefSeq, Dec 2010]

Human, Mouse

2°C to 8°C

12352203